Welcome
Welcome to USC Stem Cell, a university wide initiative connecting researchers and highlighting the latest news in regenerative medicine across USC.
April 26, 2013
Novel Role for an Ancient Pathway Discovered
Wnt Pathway in Maintaining Stem Cell Fate
Recent work from the McMahon group sheds new light on the molecular processes balancing the maintenance of embryo stem cells, and their loss of stem cell properties and commitment to more specialized cell types. To read more, please click here.
April 19, 2013
Unraveling the Mystery of Pluripotency in ES Cells
Dr. Wange Lu (left) and the first author of the paper, research associate Fan Gao
Using advanced sequencing technology, Center faculty Wange Lu’s group, in collaboration with Dr. Kai Wang of Zilkha Neurogenetics Institute explores the mystery of pluripotency by mapping out the interaction between DNA elements using genetic loci of two important pluripotency genes OCT4 and SOX2. Their finding shows that chromosome elements can interact transiently and dynamically with long-range target regions on the same chromosome or a different chromosome. The study is published in Scientific Report.